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pigx

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Official Full Name
phosphatidylinositol glycan anchor biosynthesis, class X
Background
This gene encodes a type I transmembrane protein in the endoplasmic reticulum (ER). The protein is an essential component of glycosylphosphatidylinositol-mannosyltransferase I, which transfers the first of the four mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Studies in rat indicate that the protein is translated from a non-AUG translation initiation site. Alternative splicing results in multiple transcript variants.
Synonyms
PIGX; phosphatidylinositol glycan anchor biosynthesis, class X; phosphatidylinositol glycan, class X; phosphatidylinositol-glycan biosynthesis class X protein; FLJ20522; PIG-X; GPI-mannosyltransferase subunit; si:ch73-159l23.2