Official Full Name
polymeric immunoglobulin receptor
This gene is a member of the immunoglobulin superfamily. The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells; the complex is then transported across the cell to be secreted at the apical surface. A significant association was found between immunoglobulin A nephropathy and several SNPs in this gene.
PIGR; polymeric immunoglobulin receptor; poly-Ig receptor; hepatocellular carcinoma associated protein TB6; hepatocellular carcinoma-associated protein TB6; FLJ22667; MGC125361; MGC125362; si:ch211-9d9.6