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pigk

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Official Full Name
phosphatidylinositol glycan anchor biosynthesis, class K
Background
This gene encodes a member of the cysteine protease family C13 that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is a member of the multisubunit enzyme, GPI transamidase and is thought to be its enzymatic component. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins.
Synonyms
PIGK; phosphatidylinositol glycan anchor biosynthesis, class K; phosphatidylinositol glycan, class K; GPI-anchor transamidase; GPI transamidase subunit; GPI8; hGPI8; PIG-K; GPI8 homolog; phosphatidylinositol-glycan biosynthesis class K protein; MGC22559; zgc:86702

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