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pgd

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Official Full Name
phosphogluconate dehydrogenase
Background
6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies.
Synonyms
PGD; phosphogluconate dehydrogenase; 6-phosphogluconate dehydrogenase, decarboxylating; 6PGD; fi03d03; zgc:55585; wu:fi03d03; zgc:111848; phosphogluconate hydrogenase