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pfkp

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Official Full Name
phosphofructokinase, platelet
Background
The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK);(ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of;fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which;maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM; MIM 610681) and liver (PFKL; MIM;171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981) (PubMed;6451249) determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits;P4, P3L, and P2L2.
Synonyms
PFKP; phosphofructokinase, platelet; 6-phosphofructokinase type C; PFK C; PFKF; Phosphofructokinase; platelet type; phosphohexokinase; phosphofructokinase 1; phosphofructo-1-kinase isozyme C; Phosphofructokinase, platelet type; 6-phosphofructokinase, plat; 6-phosphofructokinase, platelet type; PFK-C; FLJ40226; FLJ44165; PFKF, PFK-C; PFKM; PFK-P; ATP-PFK