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pex26

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Official Full Name
peroxisomal biogenesis factor 26
Background
This gene belongs to the peroxin-26 gene family. It is probably required for protein import into peroxisomes. It anchors PEX1 and PEX6 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes. Defects in this gene are the cause of peroxisome biogenesis disorder complementation group 8 (PBD-CG8). PBD refers to a group of peroxisomal disorders arising from a failure of protein import into the peroxisomal membrane or matrix. The PBD group is comprised of four disorders: Zellweger syndrome (ZWS), neonatal adrenoleukodystrophy (NALD), infantile Refsum disease (IRD), and classical rhizomelic chondrodysplasia punctata (RCDP). Alternatively spliced transcript variants have been identified for this gene.
Synonyms
PEX26; peroxisomal biogenesis factor 26; peroxisome biogenesis factor 26; peroxisome assembly protein 26; FLJ20695; AI85321; 4632428M11Rik; OTTMUSP00000033411; OTTMUSP00000033413; Peroxin 26; Peroxisome biogenesis disorder, complementation group 8; Peroxisome biogenesis disorder, complementation group A; PEX 26; Pex26pM1T; peroxin-26; PEX26M1T; PBD7A, PBD7B, PEX26M1T, Pex26pM1T; fk41g06; zgc:64014; wu:fk41g06

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