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pex14

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Official Full Name
peroxisomal biogenesis factor 14
Background
This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome.
Synonyms
PEX14; peroxisomal biogenesis factor 14; peroxisomal membrane protein PEX14; NAPP2; NF E2 associated polypeptide 2; Peroxin 14; Peroxin-14; Peroxisomal membrane anchor protein PEX14; PEX14_HUMAN; Pex14p; PTS1 receptor docking protein; PTS1 receptor-docking protein; OTTHUMP00000001902; NF-E2 associated polypeptide 2; peroxisomal membrane anchor protein Pex14p; dJ734G22.2; MGC12767; NAPP2, PBD13A, Pex14p, dJ734G22.2

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