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pelp1

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Official Full Name
proline, glutamate and leucine rich protein 1
Background
This gene encodes a transcription factor which coactivates transcription of estrogen receptor responsive genes and corepresses genes activated by other hormone receptors or sequence-specific transcription factors. Expression of this gene is regulated by both members of the estrogen receptor family. This gene may be involved in the progression of several types of cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
Synonyms
PELP1; proline, glutamate and leucine rich protein 1; MNAR; P160; proline-, glutamic acid- and leucine-rich protein 1; transcription factor HMX3; proline and glutamic acid rich nuclear protein; modulator of non-genomic activity of estrogen receptor

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