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peli3

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Official Full Name
pellino E3 ubiquitin protein ligase family member 3
Background
The protein encoded by this gene is a scaffold protein and an intermediate signaling protein in the innate immune response pathway. The encoded protein helps transmit the immune response signal from Toll-like receptors to IRAK1/TRAF6 complexes. Several transcript variants encoding different isoforms have been found for this gene.
Synonyms
PELI3; pellino homolog 3 (Drosophila); E3 ubiquitin-protein ligase pellino homolog 3; MGC35521; E3 ubiquitin protein ligase pellino homolog 3; PEL 13; PELI3_HUMAN; Pellino 3; Pellino 3 alpha; Pellino-3; Protein pellino homolog 3; pellino E3 ubiquitin protein ligase family member 3; pellino homolog 3