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pdk1

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Official Full Name
pyruvate dehydrogenase kinase, isozyme 1
Background
Phosphoinositide-dependent protein kinase 1 (PDK-1) plays a central role in many signal transduction pathways, activating AKT and the PKC isoenzyme p70S6 kinase and RSK. Through its effects on these kinases, PDK-1 is involved in the regulation of wide variety of process, including cell proliferation, differentiation and apoptosis.
Synonyms
PDK1; pyruvate dehydrogenase kinase, isozyme 1; pyruvate dehydrogenase kinase, isoenzyme 1; mitochondrial pyruvate dehydrogenase, lipoamide, kinase isoenzyme 1

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