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pcm1

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Official Full Name
pericentriolar material 1
Background
The protein encoded by this gene is a component of centriolar satellites, which are electron dense granules scattered around centrosomes. Inhibition studies show that this protein is essential for the correct localization of several centrosomal proteins, and for anchoring microtubules to the centrosome. Chromosomal aberrations involving this gene are associated with papillary thyroid carcinomas and a variety of hematological malignancies, including atypical chronic myeloid leukemia and T-cell lymphoma.
Synonyms
PCM1; pericentriolar material 1; pericentriolar material 1 protein; PTC4; hPCM-1; PCM-1; PCM1_HUMAN; OTTHUMP00000224566; OTTHUMP00000224569; OTTHUMP00000224570; pericentriolar material 1, PCM1; pericentriolar material-1; wu:fb30g01; wu:fb94e03; wu:fe14f07