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pcdh8

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Official Full Name
protocadherin 8
Background
This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes an integral membrane protein that is thought to function in cell adhesion in a CNS-specific manner. Unlike classical cadherins, which are generally encoded by 15-17 exons, this gene includes only 3 exons. Notable is the large first exon encoding the extracellular region, including 6 cadherin domains and a transmembrane region. Alternative splicing yields isoforms with unique cytoplasmic tails.
Synonyms
PCDH8; protocadherin 8; protocadherin-8; ARCADLIN; PAPC; paraxial protocadherin 8 short isoform; zPAPC; paraxial protocadherin

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