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pcdh11y

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Official Full Name
protocadherin 11 Y-linked
Background
This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 7 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene is located in a major X/Y block of homology and its most closely related cadherin superfamily member is located in this homologous region on the X chromosome. The protein is thought to play a fundamental role in cell-cell recognition essential for the segmental development and function of the central nervous system. Transcripts arising from alternative splicing encode isoforms with N- and C-terminal variation.
Synonyms
PCDH11Y; protocadherin 11 Y-linked; PCDH22, protocadherin 22; protocadherin-11 Y-linked; PCDHY; PCDH 11; PCDH 11X; PCDH 11Y; PCDH 22; PCDH PC; PCDH Y; PCDH11; PCDH11X; PCDH22; Protocadherin 11; Protocadherin 11 X linked; Protocadherin 11 Y linked; Protocadherin 22; Protocadherin on the Y chromosome; Protocadherin PC; Protocadherin prostate cancer; Protocadherin Y; Protocadherin11; Protocadherin22; ProtocadherinY; PCDH-Y; protocadherin-22; protocadherin-PC; OTTHUMP00000033076; OTTHUMP00000033077; OTTHUMP00000033078; PCDH-PC