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pam

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Official Full Name
peptidylglycine alpha-amidating monooxygenase
Background
This gene encodes a multifunctional protein. It has two enzymatically active domains with catalytic activities - peptidylglycine alpha-hydroxylating monooxygenase (PHM) and peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL). These catalytic domains work sequentially to catalyze neuroendocrine peptides to active alpha-amidated products. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene but some of their full length sequences are not yet known.
Synonyms
PAM; peptidylglycine alpha-amidating monooxygenase; peptidyl-glycine alpha-amidating monooxygenase; PAL; peptidyl alpha hydroxyglycine alpha amidating lyase; peptidylglycine alpha hydroxylating monooxygenase; PHM; AMD_HUMAN; Pancreatic peptidylglycine alpha amidating monooxygenase; Peptidyl alpha amidating enzyme; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase; Peptidylamidoglycolate lyase; Peptidylglycine 2 hydroxylase; Peptidylglycine alpha amidating monooxygenase; OTTHUMP00000158920; OTTHUMP00000158921; OTTHUMP00000158922; OTTHUMP00000158923; OTTHUMP00000222752; OTTHUMP00000227957; peptidylglycine 2-hydroxylase; peptidyl alpha-amidating enzyme; pep; peptidylglycine alpha-hydroxylating monooxygenase; pancreatic peptidylglycine alpha-amidating monooxygenase

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