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paip2b

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Official Full Name
poly(A) binding protein interacting protein 2B
Background
Most mRNAs, except for histones, contain a 3-prime poly(A) tail. Poly(A)-binding protein (PABP; see MIM 604679);enhances translation by circularizing mRNA through its interaction with the translation initiation factor EIF4G1 (MIM;600495) and the poly(A) tail. Various PABP-binding proteins regulate PABP activity, including PAIP1 (MIM 605184), a;translational stimulator, and PAIP2A (MIM 605604) and PAIP2B, translational inhibitors (Derry et al., 2006 (PubMed;17381337)).
Synonyms
PAIP2B; poly(A) binding protein interacting protein 2B; polyadenylate-binding protein-interacting protein 2B; KIAA1155; PABP-interacting protein 2B; PAI2B_HUMAN; PAIP-2B; Poly(A)-binding protein-interacting protein 2B; zgc:73265; paip2

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