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pafah2

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Official Full Name
platelet-activating factor acetylhydrolase 2, 40kDa
Background
This gene encodes platelet-activating factor acetylhydrolase isoform 2, a single-subunit intracellular enzyme that catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). However, this lipase exhibits a broader substrate specificity than simply platelet activating factor. Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist, and both are multi-subunit enzymes. Additionally, there is a single-subunit serum isoform of this enzyme.
Synonyms
PAFAH2; platelet-activating factor acetylhydrolase 2, 40kDa; platelet activating factor acetylhydrolase 2 (40kD); platelet-activating factor acetylhydrolase 2, cytoplasmic; HSD PLA2; EC 3.1.1.47; HSDPLA2; Platelet activating factor acetylhydrolase 2; Serine dependent phospholipase A2; SD-PLA2; serine-dependent phospholipase A2; HSD-PLA2

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