Official Full Name
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
The product of this gene belongs to the family of prolyl 4-hydroxylases. This protein is a prolyl hydroxylase that may be involved in the degradation of hypoxia-inducible transcription factors under normoxia. It plays a role in adaptation to hypoxia and may be related to cellular oxygen sensing. Alternatively spliced variants encoding different isoforms have been identified.
P4HTM; prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum); transmembrane prolyl 4-hydroxylase; EGLN4; FLJ20262; HIFPH4; hypoxia inducible factor prolyl 4 hydroxylase; P4H TM; PH 4; PH4; PHD4; Prolyl hydroxlase domain containing 4; HIF prolyl hydroxylase PH4; HIF-PH4; HIF-prolyl hydroxylase 4; HPH-4; Hypoxia inducible factor prolyl hydroxylase; Hypoxia-inducible factor prolyl hydroxylase 4; P4H with transmembrane domain; P4H-TM; P4HTM_HUMAN; Proline 4 hydroxylase; Prolyl 4 hydroxylase transmembrane (endoplasmic reticulum); OTTHUMP00000082685; OTTHUMP00000082686; proline 4-hydroxylase; Prolyl hydroxlase domain-containing 4; hypoxia; PH-4; hypoxia-inducible factor prolyl 4-hydroxylase