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p4ha3

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Official Full Name
prolyl 4-hydroxylase, alpha polypeptide III
Background
This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.
Synonyms
P4HA3; prolyl 4-hydroxylase, alpha polypeptide III; procollagen proline, 2 oxoglutarate 4 dioxygenase (proline 4 hydroxylase), alpha polypeptide III; prolyl 4-hydroxylase subunit alpha-3; C P4Halpha(III); collagen prolyl 4 hydroxylase alpha(III); 4-PH alpha-3; Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide III; Procollagen-proline, 2-oxoglutarate 4-dioxygenase, alpha subunit, isoform 3; Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-3; Prolyl 4-hydroxylase, alpha-3 subunit; C-P4H alpha III; collagen prolyl 4-hydroxylase alpha(III)

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