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p2rx1

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Official Full Name
purinergic receptor P2X, ligand-gated ion channel, 1
Background
The protein encoded by this gene belongs to the P2X family of G-protein-coupled receptors. These proteins can form homo-and heterotimers and function as ATP-gated ion channels and mediate rapid and selective permeability to cations. This protein is primarily localized to smooth muscle where binds ATP and mediates synaptic transmission between neurons and from neurons to smooth muscle and may being responsible for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. This protein may also be involved in promoting apoptosis. [provided by RefSeq, Jun 2013]
Synonyms
P2RX1; purinergic receptor P2X, ligand-gated ion channel, 1; P2X1; P2X purinoceptor 1; ATP receptor; P2X1 receptor; P2X receptor, subunit 1; purinergic receptor P2X1; p2xr1; zP2X1_tv1