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os9

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Official Full Name
osteosarcoma amplified 9, endoplasmic reticulum lectin
Background
This gene encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Synonyms
OS9; osteosarcoma amplified 9, endoplasmic reticulum lectin; OS-9; ERLEC2; protein OS-9; erlectin 2; amplified in osteosarcoma 9; endoplasmic reticulum lectin 2; osteosarcoma amplified 9, endoplasmic reticulum associated protein; OS 9; zgc:153838; amplified in osteosarcoma

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