Tel: 1-631-626-9181 (USA)   44-207-097-1828 (Europe)

CBpromise   

Our promise to you:
Guaranteed product quality, expert customer support.

24x7 CUSTOMER SERVICE
CONTACT US TO ORDER

oat

Bookmark and Share
Official Full Name
ornithine aminotransferase
Background
This gene encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Alternatively spliced transcript variants encoding different isoforms have been described. Related pseudogenes have been defined on the X chromosome.
Synonyms
OAT; ornithine aminotransferase; ornithine aminotransferase, mitochondrial; gyrate atrophy; HOGA; ornithine aminotransferase precursor; GACR; OATASE; OKT; Ornithine aminotransferase (gyrate atrophy); Ornithine aminotransferase mitochondrial; Ornithine aminotransferase, mitochondrial precursor; Ornithine delta aminotransferase; Ornithine oxo acid aminotransferase; OTTHUMP00000020690; ornithine delta-aminotransferase; ornithine-delta-aminotransferase; ornithine-oxo-acid aminotransferase; ornithine--oxo-acid aminotransferase; DKFZp781A11155; organic anion transporter; slc22a6; zgc:77073; solute carrier family 22 member 6; ROAT1; zfOat; organic anion transporter 1; renal organic anion transporter 1