This gene encodes a nucleotidase that catalyzes the dephosphorylation of the 5 deoxyribonucleotides (dNTP) and 2(3)-dNTP and ribonucleotides, but not 5 ribonucleotides. Of the different forms of nucleotidases characterized, this enzyme is unique in its preference for 5-dNTP. It may be one of the enzymes involved in regulating the size of dNTP pools in cells. Alternatively spliced transcript variants have been found for this gene.
NT5C; 5, 3-nucleotidase, cytosolic; 5 nucleotidase, deoxy (pyrimidine), cytosolic type C , UMPH2, uridine 5 prime monophosphate hydrolase 2; 5(3)-deoxyribonucleotidase, cytosolic type; cdN; DNT 1; DNT1; PN I; deoxy-5-nucleotidase 1; cytosolic 5,3-; cytosolic 5,3-pyrimidine nucleotidase; uridine 5-prime monophosphate hydrolase 2; uridine 5-monophosphate phosphohydrolase 2; 5 nucleotidase, deoxy (pyrimidine), cytosolic type C; DNT; P5N2; PN-I; PN-II; UMPH2; dNT-1