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nsun2

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Official Full Name
NOP2/Sun RNA methyltransferase family, member 2
Background
This gene encodes a methyltransferase that catalyzes the methylation of cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA(Leu)(CAA) precursors. This modification is necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Synonyms
NSUN2; NOP2/Sun domain family, member 2; NOL1/NOP2/Sun domain family 2 , NOL1/NOP2/Sun domain family, member 2; tRNA (cytosine(34)-C(5))-methyltransferase; FLJ20303; Misu; Myc induced SUN domain containing protein; TRM4; tRNA methyltransferase 4 homolog; tRNA methyltransferase 4 homolog (S. cerevisiae); hTrm4; NOL1/NOP2/Sun domain family 2; substrate of AIM1/Aurora kinase B; 5-methycytoisine methyltransferase; NOL1/NOP2/Sun domain family member 2; NOL1/NOP2/Sun domain family, member 2; Myc-induced SUN-domain-containing protein; myc-induced SUN domain-containing protein; tRNA (cytosine-5-)-methyltransferase NSUN2; SAKI; NOP2/Sun RNA methyltransferase family, member 2; zgc:55517; wu:fc65a08