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nsmaf

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Official Full Name
neutral sphingomyelinase (N-SMase) activation associated factor
Background
This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.
Synonyms
NSMAF; neutral sphingomyelinase (N-SMase) activation associated factor; protein FAN; FAN; Factor associated with N SMase activation; Factor associated with neutral sphingomyelinase; Factor associated with neutral sphingomyelinase activation; Neutral sphingomyelinase (N SMase) activation associated factor; OTTHUMP00000226511; OTTHUMP00000226512; factor associated with N-SMase activation