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nr4a3

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Official Full Name
nuclear receptor subfamily 4, group A, member 3
Background
This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as;a transcriptional activator. The protein can efficiently bind the NGFI-B Response Element (NBRE). Three different;versions of extraskeletal myxoid chondrosarcomas (EMCs) are the result of reciprocal translocations between this gene;and other genes. The translocation breakpoints are associated with Nuclear Receptor Subfamily 4, Group A, Member 3 (on;chromosome 9) and either Ewing Sarcome Breakpoint Region 1 (on chromosome 22), RNA Polymerase II, TATA Box-Binding;Protein-Associated Factor, 68-KD (on chromosome 17), or Transcription factor 12 (on chromosome 15). Multiple;transcript variants encoding different isoforms have been found for this gene.
Synonyms
NR4A3; nuclear receptor subfamily 4, group A, member 3; nuclear receptor subfamily 4 group A member 3; CHN; CSMF; MINOR; NOR1; Chondrosarcoma, extraskeletal myxoid, fused to EWS; Mitogen induced nuclear orphan receptor; Mitogen-induced nuclear orphan receptor; Neuron derived orphan receptor 1; Neuron derived orphan receptor; Neuron-derived orphan receptor 1; NR4A3_HUMAN; Nuclear hormone receptor NOR-1; Nuclear hormone receptor NOR1; TEC; Translocated in extraskeletal chondrosarcoma; OTTHUMP00000022774; OTTHUMP00000022775; OTTHUMP00000022776; cho; neural orphan nuclear receptor NOR1

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