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nox5

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Official Full Name
NADPH oxidase, EF-hand calcium binding domain 5
Background
This gene is predominantly expressed in the testis and lymphocyte-rich areas of spleen and lymph nodes. It encodes a calcium-dependen NADPH oxidase that generates superoxide, and functions as a calcium-dependent proton channel that may regulate redox-dependent processes in lymphocytes and spermatozoa. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Synonyms
NOX5; NADPH oxidase, EF-hand calcium binding domain 5; NADPH oxidase 5; NOX5A; NOX5B; MGC149776; MGC149777

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