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nova1

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Official Full Name
neuro-oncological ventral antigen 1
Background
This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described.
Synonyms
NOVA1; neuro-oncological ventral antigen 1; RNA-binding protein Nova-1; ventral neuron-specific protein 1; Nova-1; G630039L02; 9430099M15Rik; si:ch211-222c22.9

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