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nostrin

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Official Full Name
nitric oxide synthase trafficking
Background
Nitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission, inflammatory response, and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production, endothelial NO synthase (ENOS; MIM 163729), and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures, thereby attenuating ENOS-dependent NO production.
Synonyms
NOSTRIN; nitric oxide synthase trafficker; MGC20702; BM247; BM247 homolog; DaIP2; eNOS-trafficking inducer; mDaIP2; Nitric oxide synthase traffic inducer; NOSTN_HUMAN; RP23-431D4.2; ENOS traffic inducer; nitric oxide synthase trafficking; endothelial nitric oxide synthase traffic inducer; ortholog of mouse disabled 2 interacting proein 2; DaIP2, MGC20702, NOSTRIN

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