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nlrp2

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Official Full Name
NLR family, pyrin domain containing 2
Background
NALP proteins, such as NALP2, are characterized by an N-terminal pyrin (MIM 608107) domain (PYD) and are involved in;the activation of caspase-1 (CASP1; MIM 147678) by Toll-like receptors (see TLR4; MIM 603030). They may also be;involved in protein complexes that activate proinflammatory caspases (Tschopp et al., 2003 (PubMed;12563287)).
Synonyms
NLRP2; NLR family, pyrin domain containing 2; NACHT, leucine rich repeat and PYD containing 2 , NALP2; NACHT, LRR and PYD domains-containing protein 2; CLR19.9; FLJ20510; NBS1; nucleotide binding oligomerization domain; leucine rich repeat and pyrin domai; leucine rich repeat and pyrin domain containing 2; PAN1; PYPAF2; nucleotide-binding site protein 1; PYRIN-containing APAF1-like protein 2; NACHT, LRR and PYD containing protein 2; NACHT, leucine rich repeat and PYD containing 2; PYRIN domain and NACHT domain-containing protein 1; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 2; NALP2