Official Full Name
NFS1 cysteine desulfurase
Iron-sulfur clusters are required for the function of many cellular enzymes. The proteins encoded by this gene supply inorganic sulfur to these clusters by removing the sulfur from cysteine, creating alanine in the process. This gene uses alternate in-frame translation initiation sites to generate mitochondrial forms and cytoplasmic/nuclear forms. Selection of the alternative initiation sites is determined by the cytosolic pH. The encoded proteins belong to the class-V family of pyridoxal phosphate-dependent aminotransferases. Alternatively spliced transcript variants have been described.
NFS1; NFS1 nitrogen fixation 1 homolog (S. cerevisiae); nitrogen fixation 1 (S. cerevisiae, homolog); cysteine desulfurase, mitochondrial; IscS; NifS; HUSSY 08; nitrogen fixation gene 1; OTTHUMP00000030799; OTTHUMP00000030800; OTTHUMP00000179026; nitrogen-fixing bacteria S-like protein; HUSSY-08; NFS1 cysteine desulfurase; NFS1 nitrogen fixation 1 homolog; fb50g03; wu:fb50g03; NFS1 nitrogen fixation 1