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nedd9

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Official Full Name
neural precursor cell expressed, developmentally down-regulated 9
Background
The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Synonyms
NEDD9; neural precursor cell expressed, developmentally down-regulated 9; CAS2; CASL; HEF1; CAS-L; CASS2; enhancer of filamentation 1; cas-like docking; p130Cas-related protein; Enhancer of filamentation 1 p55; renal carcinoma antigen NY-REN-12; Cas scaffolding protein family member 2; Crk-associated substrate related protein Cas-L; neural precursor cell expressed developmentally down-regulated protein 9; CAS L; Cas like; p105; NEDD-9; Crk-associated substrate related; CRK-associated substrate-related protein; dJ761I2.1 (enhancer of filamentation (HEF1)); dJ49G10.2 (Enhancer of Filamentation 1 (HEF1)); dJ49G10.2; dJ761I2.1; wu:fc45g12; zgc:154043; fc45g12; neural precursor cell expressed, developmentally down-regulated gene 9