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nebl

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Official Full Name
nebulette
Background
This gene encodes a nebulin like protein that is abundantly expressed in cardiac muscle. The encoded protein binds actin and interacts with thin filaments and Z-line associated proteins in striated muscle. This protein may be involved in cardiac myofibril assembly. A shorter isoform of this protein termed LIM nebulette is expressed in non-muscle cells and may function as a component of focal adhesion complexes. Alternate splicing results in multiple transcript variants.
Synonyms
NEBL; nebulette; LIM-nebulette; actin-binding Z-disk protein; LASP2; LNEBL; FLJ53769; MGC119746; MGC119747; LASP-2; LIM and SH3 protein; zgc:113144

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