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ndufs7

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Official Full Name
NADH dehydrogenase (ubiquinone) Fe-S protein 7, (NADH-coenzyme Q reductase)
Background
This gene encodes a protein that is a subunit of one of the complexes that forms the mitochondrial respiratory chain.;This protein is one of over 40 subunits found in complex I, the nicotinamide adenine dinucleotide (NADH):ubiquinone;oxidoreductase. This complex functions in the transfer of electrons from NADH to the respiratory chain, and ubiquinone;is believed to be the immediate electron acceptor for the enzyme. Mutations in this gene cause Leigh syndrome due to;mitochondrial complex I deficiency, a severe neurological disorder that results in bilaterally symmetrical necrotic;lesions in subcortical brain regions.
Synonyms
NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase); NADH dehydrogenase (ubiquinone) Fe S protein 7 (20kD) (NADH coenzyme Q reductase); CI 20; complex I 20kDa subunit; FLJ45860; FLJ46880; NADH dehydrogenase [ubiquinon; PSST; CI-20; MY017; CI-20KD; NADH dehydrogenase (ubiquinone) Fe-S protein 7, (NADH-coenzyme Q reductase); im:7149436; NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial

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