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ndufa2

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Official Full Name
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
Background
The encoded protein is a subunit of the hydrophobic protein fraction of the NADH:ubiquinone oxidoreductase (complex 1), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane, and may be involved in regulating complex I activity or its assembly via assistance in redox processes. Mutations in this gene are associated with Leigh syndrome, an early-onset progressive neurodegenerative disorder. Alternative splicing results in multiple transcript variants.
Synonyms
NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2 (8kD, B8); NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; B8; complex I B8 subunit; CD 14; CD14; CI B8; Complex I B8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 2 8kDa; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 2; NADH ubiquinone oxidoreductase B8 subunit; NDUFA 2; OTTHUMP00000159890; OTTHUMP00000223709; NADH-ubiquinone oxidoreductase subunit CI-B8; CIB8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2; zgc:112340

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