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ndp

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Official Full Name
Norrie disease (pseudoglioma)
Background
This gene encodes a secreted protein with a cystein-knot motif that activates the Wnt/beta-catenin pathway. The protein forms disulfide-linked oligomers in the extracellular matrix. Mutations in this gene result in Norrie disease and X-linked exudative vitreoretinopathy.
Synonyms
NDP; Norrie disease (pseudoglioma); EVR2, exudative vitreoretinopathy 2 (X linked); norrin; EVR2; Exudative vitreoretinopathy 2 (X linked); FEVR; ND; NDP_HUMAN; Norrie disease protein; Norrin precursor; X linked exudative vitreoretinopathy 2 protein; X-linked exudative vitreoretinopathy 2 protein

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