This gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Alternative splicing results in multiple transcript variants.
NDE1; nudE nuclear distribution gene E homolog 1 (A. nidulans); nuclear distribution protein nudE homolog 1; FLJ20101; NUDE; HOM TES 87; LIS1 interacting protein NUDE1rat homolog; LIS1 interacting protein NUDE1; NDE 1; NDE1_HUMAN; Nuclear distribution gene E homolog 1; NUDE 1; NudE nuclear distribution gene E homolog 1; NUDE1; OTTHUMP00000160329; OTTHUMP00000160330; LIS1-interacting protein NUDE1, rat homolog; LIS4; HOM-TES-87; nudE nuclear distribution E homolog 1 (A. nidulans); LIS4, NUDE, NUDE1, HOM-TES-87; nudE neurodevelopment protein 1; nudE nuclear distribution E homolog 1; fb82g01; im:7141877; wu:fb82g01; zgc:114109