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ncoa4

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Official Full Name
nuclear receptor coactivator 4
Background
This gene encodes an androgen receptor coactivator. The encoded protein interacts with the androgen receptor in a ligand-dependent manner to enhance its transcriptional activity. Chromosomal translocations between this gene and the ret tyrosine kinase gene, also located on chromosome 10, have been associated with papillary thyroid carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes are present on chromosomes 4, 5, 10, and 14.
Synonyms
NCOA4; nuclear receptor coactivator 4; ARA70; DKFZp762E1112; ELE1; PTC3; RET activating gene ELE1; RFG; NCoA-4; ret fused; 70 kDa AR-activator; RET-activating gene ELE1; 70 kDa androgen receptor coactivator; androgen receptor-associated protein of 70 kDa; zgc:55307; zgc:77270

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