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nckipsd

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Official Full Name
NCK interacting protein with SH3 domain
Background
The protein encoded by this gene is localized exclusively in the cell nucleus. It plays a role in signal transduction, and may function in the maintenance of sarcomeres and in the assembly of myofibrils into sarcomeres. It also plays an important role in stress fiber formation. The gene is involved in therapy-related leukemia by a chromosomal translocation t(3;11)(p21;q23) that involves this gene and the myeloid/lymphoid leukemia gene. Alternative splicing occurs in this locus and two transcript variants encoding distinct isoforms have been identified.
Synonyms
NCKIPSD; NCK interacting protein with SH3 domain; NCK-interacting protein with SH3 domain; AF3P21; dia interacting protein; diaphanous protein interacting protein; DIP1; ORF1; SH3 protein interacting with Nck; 90 kDa; SPIN90; WASLBP; WISH; DIP; SH3 protein interacting with Nck90 kDa; VIP54; DIP-1; OTTHUMP00000164823; OTTHUMP00000210186; dia-interacting protein 1; SH3 adapter protein SPIN90; 54 kDa VacA-interacting protein; 54 kDa vimentin-interacting protein; WASP-interacting SH3; WASP-interacting SH3-domain protein; diaphanous protein-interacting protein; 90 kDa SH3 protein interacting with Nck; SH3 protein interacting with Nck, 90 kDa; wiskott-Aldrich syndrome protein-interacting protein; MGC23891

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