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nap1l4

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Official Full Name
nucleosome assembly protein 1-like 4
Background
This gene encodes a member of the nucleosome assembly protein (NAP) family which can interact with both core and linker histones. It can shuttle between the cytoplasm and nucleus, suggesting a role as a histone chaperone. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer.
Synonyms
NAP1L4; nucleosome assembly protein 1-like 4; NAP2; Nucleosome assembly protein 2; NAP-2; nucleosome assembly protein 1-like 4b; NAP2L; hNAP2; NAP1L4b; MGC4565

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