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n4bp2

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Official Full Name
NEDD4 binding protein 2
Background
This gene encodes a protein containing a polynucleotide kinase domain (PNK) near the N-terminal region, and a Small MutS Related (Smr) domain near the C-terminal region. The encoded protein can bind to both B-cell leukemia/lymphoma 3 (BCL-3) and neural precursor cell expressed, developmentally downregulated 4, (Nedd4) proteins. This protein binds and hydrolyzes ATP, may function as a 5-polynucleotide kinase, and has the capacity to be a ubiquitylation substrate. This protein may play a role in transcription-coupled DNA repair or genetic recombination.
Synonyms
N4BP2; NEDD4 binding protein 2; NEDD4-binding protein 2; B3BP; BCL 3 binding protein; BCL3 binding protein; FLJ10680; KIAA1413; BCL-3-binding protein; zgc:153456

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