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myo9b

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Official Full Name
myosin IXB
Background
This gene encodes a member of the myosin family of actin-based molecular motor heavy chain proteins. The protein has four IQ motifs located in the neck domain that bind calmodulin, which serves as a light chain. The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end. The protein also has rho-GTPase activity. Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms
MYO9B; myosin IXB; CELIAC4; myosin-IXb; CELIAC 4; Celiac disease 4; MYO 9B; Myosin 9B; Myosin IX; Myosin9B; MyosinIX; MyosinIXB; MYR 5; MYR5; Unconventional myosin 9b; unconventional myosin-9b; unconventional myosin IXb

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