Official Full Name
myosin, heavy chain 2, skeletal muscle, adult
Myosins are actin-based motor proteins that function in the generation of mechanical force in eukaryotic cells. Muscle myosins are heterohexamers composed of 2 myosin heavy chains and 2 pairs of nonidentical myosin light chains. This gene encodes a member of the class II or conventional myosin heavy chains, and functions in skeletal muscle contraction. This gene is found in a cluster of myosin heavy chain genes on chromosome 17. A mutation in this gene results in inclusion body myopathy-3. Multiple alternatively spliced variants, encoding the same protein, have been identified.
MYH2; myosin, heavy chain 2, skeletal muscle, adult; myosin, heavy polypeptide 2, skeletal muscle, adult; myosin-2; MYH2A; MYHas8; MyHC 2A; MyHC IIa; MYHSA2; Myosin heavy chain IIa; Myosin heavy chain skeletal muscle adult 2; OTTHUMP00000160894; myosin heavy chain 2; myosin heavy chain 2a; fast 2a myosin heavy chain; type IIA myosin heavy chain; myosin heavy chain, skeletal muscle, adult 2; MyHC-2A; MyHC-IIa