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myb

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Official Full Name
v-myb avian myeloblastosis viral oncogene homolog
Background
This gene encodes a transcription factor that is a member of the MYB family of transcription factor genes. The protein contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal domain involved in transcriptional repression. This protein plays an essential role in the regulation of hematopoiesis and may play a role in tumorigenesis. Alternative splicing results in multiple transcript variants.
Synonyms
MYB; v-myb myeloblastosis viral oncogene homolog (avian); v myb avian myeloblastosis viral oncogene homolog; transcriptional activator Myb; c myb; c-myb8B_CDS; c-myb10A_CDS; c-myb13A_CDS; c-myb14A_CDS; proto-oncogene c-Myb; c-myb protein (140 AA); efg; Cm; v-myb avian myeloblastosis viral oncogene homolog; c-myb; c-myb proto-oncogene; myb proto-oncogene protein; v-myb myeloblastosis viral oncogene homolog

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