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mxd3

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Official Full Name
MAX dimerization protein 3
Background
This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators.;The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters;of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled;cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been;described.
Synonyms
MXD3; MAX dimerization protein 3; bHLHc13; MAD3; FLJ35523; Likely ortholog of mouse Max dimerization protein 3; MGC2383; MYX; OTTHUMP00000223596; OTTHUMP00000223598; max dimerizer 3; Max-associated protein 3; class C basic helix-loop-helix protein 13; Max-interacting transcriptional repressor MAD3; Mad; zgc:66281