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mtus1

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Official Full Name
microtubule associated tumor suppressor 1
Background
This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways.
Synonyms
MTUS1; microtubule associated tumor suppressor 1; mitochondrial tumor suppressor 1; microtubule-associated tumor suppressor 1; AT2 receptor interacting protein; AT2R binding protein; ATBP; ATIP1; DKFZp586D1519; FLJ14295; KIAA1288; mitochondrial tumor suppressor gene 1; MP44; MTSG1; Angiotensin II type 2 receptor interacting protein; ATIP; DKFZp686F20243; Erythroid differentiation related; GK 1; GK1; MP 44; MTSG 1; MTUS 1; Transcription factor MTSG1; OTTHUMP00000224769; OTTHUMP00000224771; OTTHUMP00000224772; OTTHUMP00000224773; AT2 receptor-binding protein; AT2 receptor-interacting protein; erythroid differentiation-r; erythroid differentiation-related; angiotensin-II type 2 receptor-interacting protein