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msl3

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Official Full Name
Homo sapiens male-specific lethal 3 homolog (Drosophila) DNA.
Background
This gene encodes a nuclear protein that is similar to the product of the Drosophila male-specific lethal-3 gene. The Drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus, the human protein is thought to play a similar function in chromatin remodeling and transcriptional regulation, and it has been found as part of a complex that is responsible for histone H4 lysine-16 acetylation. This gene can undergo X inactivation. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2, 7 and 8. [provided by RefSeq, Jul 2010]
Synonyms
MSL3; male-specific lethal 3 homolog (Drosophila); MSL3L1; male-specific lethal 3 homolog; MSL3-like 1; male-specific lethal-3 protein-like 1; male specific lethal 3 like 1 (Drosophila) , male specific lethal 3 (Drosophila) like 1 , MSL3L1; DKFZp586J1822