Official Full Name
mitochondrial ribosomal protein S7
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. In the prokaryotic ribosome, the comparable protein is thought to play an essential role in organizing the 3 domain of the 16 S rRNA in the vicinity of the P- and A-sites. Pseudogenes corresponding to this gene are found on chromosomes 8p and 12p.
MRPS7; mitochondrial ribosomal protein S7; 28S ribosomal protein S7, mitochondrial; MRP S; RP S7; RPMS7; 28S ribosomal protein S7, mitochondrial precursor; 30S ribosomal protein S7 homolog; bMRP 27a; bMRP27a; MRP S7; MRPS; RPS7; S7mt; bMRP-27a; MRP-S; RP-S7; MRP-S7; Rpms7, MRP-S7; zgc:110673