Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that has been called mitochondrial ribosomal protein S35 in the literature.
MRPS28; mitochondrial ribosomal protein S28; 28S ribosomal protein S28, mitochondrial; HSPC007; MRP S28; MRPS35; Mitochondrial 28S ribosomal protein S35; MRPS 28; S28mt; S35mt; 28S ribosomal protein S35, mitochondrial; MRP-S28; MRP-S35; FLJ22853; zgc:152965