Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that may be a functional partner of the death associated protein 3 (DAP3).
MRPS27; mitochondrial ribosomal protein S27; 28S ribosomal protein S27, mitochondrial; KIAA0264; Mitochondrial 28S ribosomal protein S27; MRP-S27; S27mt; OTTHUMP00000126943; OTTHUMP00000223555; OTTHUMP00000223883; OTTHUMP00000226223; FLJ21764; FLJ23348; FLJ38645; zgc:100970