Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. A pseudogene corresponding to this gene is found on chromosome 4.
MRPS25; mitochondrial ribosomal protein S25; 28S ribosomal protein S25, mitochondrial; DKFZp313H0817; FLJ00023; mitochondrial 28S ribosomal protein S25; MRP S25; RPMS25; 28S ribosomal protein S25 mitochondrial; S25mt; OTTHUMP00000160273; OTTHUMP00000208264; OTTHUMP00000208265; OTTHUMP00000208266; OTTHUMP00000209537; MRP-S25; zgc:110709; DKEYP-87A12.5